Detalhe da pesquisa
1.
Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials.
Lancet
; 403(10428): 741-755, 2024 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342126
2.
Pharmacokinetics and ADME Characterization of Intravenous and Oral [14C]-Linerixibat in Healthy Male Volunteers.
Drug Metab Dispos
; 49(12): 1109-1117, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625435
3.
ONO-7684 a novel oral FXIa inhibitor: Safety, tolerability, pharmacokinetics and pharmacodynamics in a first-in-human study.
Br J Clin Pharmacol
; 87(8): 3177-3189, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450079
4.
Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.
Br J Clin Pharmacol
; 87(10): 3949-3960, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33759250
5.
A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071044
6.
Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [11C]PHNO PET.
Neuropsychopharmacology
; 47(7): 1405-1412, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675381
7.
Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 7(8): 860-870, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29870591
8.
Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 7(8): 844-859, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044899